Publication

Publications before starting independent research

25. Tang, F. K., Yu, Z. H., Wong, T. H.-F., Chung, C. Y.-S., Hirao, H., & Au-Yeung, H. Y. (2020). Fluorescein-Containing Superoxide Probes with a Modular Copper-Based Trigger. ChemPlusChem, 85(4), 653–658. https://doi.org/10.1002/cplu.202000059

24. Chung, C. Y.-S.,† Posimo, J. M.,† Lee, S.,† Tsang, T.,† Davis, J. M., Brady, D. C.,# & Chang, C. J.# (2019). Activity-based ratiometric FRET probe reveals oncogene-driven changes in labile copper pools induced by altered glutathione metabolism. Proceedings of the National Academy of Sciences, 116(37), 18285. https://doi.org/10.1073/pnas.1904610116 (†These authors contributed equally; #co-corresponding authorship)

24. Chung, C. Y.-S.,† Posimo, J. M.,† Lee, S.,† Tsang, T.,† Davis, J. M., Brady, D. C.,# & Chang, C. J.# (2019). Activity-based ratiometric FRET probe reveals oncogene-driven changes in labile copper pools induced by altered glutathione metabolism. Proceedings of the National Academy of Sciences, 116(37), 18285. https://doi.org/10.1073/pnas.1904610116 (†These authors contributed equally; #co-corresponding authorship)

23. Chung, C. Y.-S.,† Shin, H. R.,† Berdan, C. A., Ford, B., Ward, C. C., Olzmann, J. A., Zoncu, R.,# & Nomura, D. K.# (2019). Covalent targeting of the vacuolar H+-ATPase activates autophagy via mTORC1 inhibition. Nature Chemical Biology, 15(8), 776–785. https://doi.org/10.1038/s41589-019-0308-4 (†These authors contributed equally; #co-corresponding authorship)

**Featured in News and Views in Nat. Chem. Biol., 2019, 15, 760)

22. Ward, C. C., Kleinman, J. I., Brittain, S. M., Lee, P. S., Chung, C. Y.-S., Kim, K., Petri, Y., Thomas, J. R., Tallarico, J. A., McKenna, J. M., Schirle, M., & Nomura, D. K. (2019). Covalent Ligand Screening Uncovers a RNF4 E3 Ligase Recruiter for Targeted Protein Degradation Applications. ACS Chemical Biology, 14(11), 2430–2440. https://doi.org/10.1021/acschembio.8b01083

21. Chung, C.Y.-S., Timblin, G. A., Saijo, K., & Chang, C. J. (2018). Versatile Histochemical Approach to Detection of Hydrogen Peroxide in Cells and Tissues Based on Puromycin Staining. Journal of the American Chemical Society, 140(19), 6109–6121. https://doi.org/10.1021/jacs.8b02279

20. Yu, Z. H.,† Chung, C. Y.-S.,† Tang, F. K.,† Brewer, T. F., & Au-Yeung, H. Y. (2017). A modular trigger for the development of selective superoxide probes. Chemical Communications, 53(72), 10042–10045. https://doi.org/10.1039/C7CC05405J († These authors contributed equally)

19. Siu, S. K.-L., Chung, C. Y.-S., & Yam, V. W.-W. (2017). Amphiphilic oligo(ethylene glycol)- and poly(ethyleneoxide)-block-poly(propylene oxide)-block-poly-(ethylene oxide)-containing cyclometalated alkynylgold(III) complexes: From basic photophysics to self-assembly and stimuli-responsive properties. Journal of Organometallic Chemistry, 845, 177–188. https://doi.org/10.1016/j.jorganchem.2017.04.035

18. Cheng, H.-K., Chung, C. Y.-S., Zhang, K., & Yam, V. W.-W. (2017). Simple and Versatile Preparation of Luminescent Amphiphilic Platinum(II)-containing Polystyrene Complexes With Transformable Nanostructures Assisted by Pt⋅⋅⋅Pt and π–π Interactions. Chemistry – An Asian Journal, 12(13), 1509–1516. https://doi.org/10.1002/asia.201700123

17. Chung, C. Y.-S., Fung, S.-K., Tong, K.-C., Wan, P.-K., Lok, C.-N., Huang, Y., Chen, T., & Che, C.-M. (2017). A multi-functional PEGylated gold(iii) compound: Potent anti-cancer properties and self-assembly into nanostructures for drug co-delivery. Chemical Science, 8(3), 1942–1953. https://doi.org/10.1039/C6SC03210A

16. Fong, T. T.-H., Lok, C.-N., Chung, C. Y.-S., Fung, Y.-M. E., Chow, P.-K., Wan, P.-K., & Che, C.-M. (2016). Cyclometalated Palladium(II) N-Heterocyclic Carbene Complexes: Anticancer Agents for Potent In Vitro Cytotoxicity and In Vivo Tumor Growth Suppression. Angewandte Chemie International Edition, 55(39), 11935–11939. https://doi.org/10.1002/anie.201602814

15. Chow, P.-K., Cheng, G., Tong, G. S. M., Ma, C., Kwok, W.-M., Ang, W.-H., Chung, C. Y.-S., Yang, C., Wang, F., & Che, C.-M. (2016). Highly luminescent palladium(ii) complexes with sub-millisecond blue to green phosphorescent excited states. Photocatalysis and highly efficient PSF-OLEDs. Chemical Science, 7(9), 6083–6098. https://doi.org/10.1039/C6SC00462H

14. Chung, C. Y.-S., Li, S. P.-Y., Lo, K. K.-W., & Yam, V. W.-W. (2016). Synthesis and Electrochemical, Photophysical, and Self-Assembly Studies on Water-Soluble pH-Responsive Alkynylplatinum(II) Terpyridine Complexes. Inorganic Chemistry, 55(9), 4650–4663. https://doi.org/10.1021/acs.inorgchem.6b00513

13. Leung, F. C.-M., Leung, S. Y.-L., Chung, C. Y.-S., & Yam, V. W.-W. (2016). Metal–Metal and π–π Interactions Directed End-to-End Assembly of Gold Nanorods. Journal of the American Chemical Society, 138(9), 2989–2992. https://doi.org/10.1021/jacs.6b01382

12. Yang, C., Mehmood, F., Lam, T. L., Chan, S. L.-F., Wu, Y., Yeung, C.-S., Guan, X., Li, K., Chung, C. Y.-S., Zhou, C.-Y., Zou, T., & Che, C.-M. (2016). Stable luminescent iridium(iii) complexes with bis(N-heterocyclic carbene) ligands: Photo-stability, excited state properties, visible-light-driven radical cyclization and CO2 reduction, and cellular imaging. Chemical Science, 7(5), 3123–3136. https://doi.org/10.1039/C5SC04458H

11. Chan, K., Chung, C. Y.-S., & Yam, V. W.-W. (2016). Parallel folding topology-selective label-free detection and monitoring of conformational and topological changes of different G-quadruplex DNAs by emission spectral changes via FRET of mPPE-Ala–Pt(ii) complex ensemble. Chemical Science, 7(4), 2842–2855. https://doi.org/10.1039/C5SC04563K

10. Chan, K., Chung, C. Y.-S., & Yam, V. W.-W. (2015). Conjugated Polyelectrolyte-Induced Self-Assembly of Alkynylplatinum(II) 2,6-Bis(benzimidazol-2′-yl)pyridine Complexes. Chemistry – A European Journal, 21(46), 16434–16447. https://doi.org/10.1002/chem.201501804

9. Chung, C. Y.-S., Tamaru, S., Shinkai, S., & Yam, V. W.-W. (2015). Supramolecular Assembly of Achiral Alkynylplatinum(II) Complexes and Carboxylic β-1,3-Glucan into Different Helical Handedness Stabilized by Pt⋅⋅⋅Pt and/or π–π Interactions. Chemistry – A European Journal, 21(14), 5447–5458. https://doi.org/10.1002/chem.201405035

8. Chung, C. Y.-S., & Yam, V. W.-W. (2014). Induced Self-Assembly of Platinum(II) Alkynyl Complexes through Specific Interactions between Citrate and Guanidinium for Proof-of-Principle Detection of Citrate and an Assay of Citrate Lyase. Chemistry – A European Journal, 20(40), 13016–13027. https://doi.org/10.1002/chem.201402137

7. Chung, C. Y.-S., & Yam, V. W.-W. (2013). Dual pH- and Temperature-Responsive Metallosupramolecular Block Copolymers with Tunable Critical Micelle Temperature by Modulation of the Self-Assembly of NIR-Emissive Alkynylplatinum(II) Complexes Induced by Changes in Hydrophilicity and Electrostatic Effects. Chemistry – A European Journal, 19(39), 13182–13192. https://doi.org/10.1002/chem.201301547

6. Chung, C. Y.-S., Li, S. P.-Y., Louie, M.-W., Lo, K. K.-W., & Yam, V. W.-W. (2013). Induced self-assembly and disassembly of water-soluble alkynylplatinum(ii) terpyridyl complexes with “switchable” near-infrared (NIR) emission modulated by metal–metal interactions over physiological pH: demonstration of pH-responsive NIR luminescent probes in cell-imaging studies. Chemical Science, 4(6), 2453–2462. https://doi.org/10.1039/C3SC50196E

5. Chung, C. Y.-S., & Yam, V. W.-W. (2013). Selective label-free detection of G-quadruplex structure of human telomere by emission spectral changes in visible-and-NIR region under physiological condition through the FRET of a two-component PPE-SO3−–Pt(ii) complex ensemble with Pt⋯Pt, electrostatic and π–π interactions. Chemical Science, 4(1), 377–387. https://doi.org/10.1039/C2SC20897K

4. Chung, C. Y.-S., & Yam, V. W.-W. (2011). Induced Self-Assembly and Förster Resonance Energy Transfer Studies of Alkynylplatinum(II) Terpyridine Complex Through Interaction With Water-Soluble Poly(phenylene ethynylene sulfonate) and the Proof-of-Principle Demonstration of this Two-Component Ensemble for Selective Label-Free Detection of Human Serum Albumin. Journal of the American Chemical Society, 133(46), 18775–18784. https://doi.org/10.1021/ja205996e

3. Hu, Y., Chan, K. H.-Y., Chung, C. Y.-S., & Yam, V. W.-W. (2011). Reversible thermo-responsive luminescent metallo-supramolecular triblock copolymers based on platinum(ii) terpyridyl chromophores with unusual aggregation behaviour and red-near-infrared (NIR) emission upon heating. Dalton Transactions, 40(45), 12228–12234. https://doi.org/10.1039/C1DT10741K

2. Chung, C. Y.-S., Chan, K. H.-Y., & Yam, V. W.-W. (2011). “Proof-of-principle” concept for label-free detection of glucose and α-glucosidase activity through the electrostatic assembly of alkynylplatinum(ii) terpyridyl complexes. Chemical Communications, 47(7), 2000–2002. https://doi.org/10.1039/C0CC04437G

1. Yam, V. W.-W., Hu, Y., Chan, K. H.-Y., & Chung, C. Y.-S. (2009). Reversible pH- and solvent-responsive micelle-mediated self-assembly of platinum(ii) terpyridyl-based metallo-supramolecular diblock copolymers. Chemical Communications, 41, 6216–6218. https://doi.org/10.1039/B911657E