Dr. Clive Yik-Sham CHUNG (PI)

Dr. Clive Yik-Sham CHUNG received first-class honors BSc degree in chemistry at The University of Hong Kong (HKU) in 2008. He then studied his PhD with Prof Vivian Wing-Wah Yam, focusing on the development of emissive platinum(II) complexes and supramolecular assemblies for biosensing, live-cell imaging and functioning as stimuli-responsive materials. After obtaining his PhD in 2013, he did his postdoctoral training with Prof. Chi-Ming Che at HKU on inorganic medicines and nano-formulations for drug delivery. In 2016, he received Croucher Postdoctoral Fellowship and moved to UC Berkeley, working with Prof Christopher J. Chang on molecular imaging to unravel roles of reactive oxygen species (ROS) and copper in biology. In 2018, he moved to Novartis-Berkeley Center for Proteomics and Chemistry Technologies in UC Berkeley, working with Prof. Daniel K. Nomura on chemoproteomics and mass spectrometry (MS) for discovering covalent ligands that can modulate autophagy and mTORC1 signaling.

In May 2020, Dr CHUNG re-joined HKU as an Assistant Professor in the School of Biomedical Sciences and Department of Pathology. His lab is now actively working in the field of chemical biology, particularly interested in: (1) studying cellular redox biology, (2) advancing proteome-wide cysteine profiling, (3) developing new therapeutic covalent ligands for targeted cancer therapy, and (4) preparation of new nanomaterials for treating cancers.